大湾区大学

董晓阳

2023/09/11 来源: 编辑:

董晓阳 | 研究员

dongxy@gbu.edu.cn

济宁医学院，药学，学士

中国药科大学，药物化学，硕士

哈尔滨工业大学，化学工程与技术，博士

科研领域

工作经历

主要成果

从事自由基不对称化学的研究。开创性地发现了铜/多齿阴离子手性单电子转移催化体系，实现了端炔与烷基卤代烃参与的自由基不对称交叉偶联反应。为自由基不对称交叉偶联提供了新的催化平台，进一步推动了自由基不对称化学的发展；
共发表 SCI 论文 16 篇，以第一作者和共同一作发表论文10篇，其中Nat. Chem.（1篇）、Chem.（1篇）、J. Am. Chem. Soc（3篇）、Angew. Chem. Int. Ed.（3篇）、Nat. Commun.（2篇），赢得了国际同行的认可与关注；
入选香江学者计划。

代表性成果

Xiao-Yang Dong,† Yu-Feng Zhang,† Can-Liang Ma,† Qiang-Shuai Gu,† Fu-Li Wang,† Zhong-Liang Li, Sheng-Peng Jiang, Xin-Yuan Liu.* A general asymmetric copper-catalysed Sonogashira C(sp3)–C(sp) coupling. Nat. Chem. 2019, 11, 1158.
Xiao-Yang Dong,† Jiang-Tao Cheng,† Yu-Feng Zhang,† Zhong-Liang Li,† Tian-Ya Zhan, Ji-Jun Chen, Fu-Li Wang, Ning-Yuan Yang, Liu Ye, Qiang-Shuai Gu, Xin-Yuan Liu.* Copper-Catalyzed Asymmetric Radical 1,2-Carboalkynylation of Alkenes with Alkyl Halides and Terminal Alkynes. J. Am. Chem. Soc. 2020, 142, 9501.
Xiao-Yang Dong,† Tian-Ya Zhan,† Sheng-Peng Jiang, Xiao-Dong Liu, Liu Ye, Zhong-Liang Li, Qiang-Shuai Gu, and Xin-Yuan Liu.* Copper-Catalyzed Asymmetric Coupling of Allenyl Radicals with Terminal Alkynes to Access Tetrasubstituted Allenes. Angew. Chem. Int. Ed. 2021, 60, 2160.
Xiao-Yang Dong, Zhong-Liang Li, Qiang-Shuai Gu, Xin-Yuan Liu.* Ligand Development for Copper-Catalyzed Enantioconvergent Radical Cross-Coupling of Racemic Alkyl Halides. J. Am. Chem. Soc. 2022, 144, 17319.
Yu-Feng Zhang†, Xiao-Yang Dong†, Jiang-Tao Cheng†, Ning-Yuan Yang, Li-Lei Wang, Fu-Li Wang, Cheng Luan, Juan Liu, Zhong-Liang Li, Qiang-Shuai Gu, and Xin-Yuan Liu*. Enantioconvergent Cu-Catalyzed Radical C−N Coupling of Racemic Secondary Alkyl Halides to Access α‑Chiral Primary Amines. J. Am. Chem. Soc. 2021, 143, 15413.